Effect of postprandial lipaemia and Taq 1B polymorphism of the cholesteryl ester transfer protein (CETP) gene on CETP mass, activity, associated lipoproteins and plasma lipids
نویسندگان
چکیده
منابع مشابه
Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
Epidemiologic studies have shown that low-density lipoprotein cholesterol (LDL-C) is a strong risk factor, whilst high-density lipoprotein cholesterol (HDL-C) reduces the risk of coronary heart disease (CHD). Therefore, strategies to manage dyslipidemia in an effort to prevent or treat CHD have primarily attempted at decreasing LDL-C and raising HDL-C levels. Cholesteryl ester transfer protein ...
متن کاملCholesteryl ester transfer protein (CETP) increases postprandial triglyceridaemia and delays triacylglycerol plasma clearance in transgenic mice.
The CETP (cholesteryl ester transfer protein) is a plasma protein synthesized in several tissues, mainly in the liver; CETP reduces plasma HDL (high-density lipoprotein) cholesterol and increases the risk of atherosclerosis. The effect of CETP levels on postprandial intravascular metabolism of TAGs (triacylglycerols) is an often-overlooked aspect of the relationship between CETP and lipoprotein...
متن کاملTaq1B polymorphism of cholesteryl ester transfer protein (CETP) gene in primary combined hyperlipidaemia.
BACKGROUND & OBJECTIVE Cholesteryl ester transfer protein (CETP) gene polymorphism is known to be associated with changes in lipid profiles. Primary hyperlipidaemia is considered to be a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. We investigated the association of one common polymorphism in the CETP gene (Taq1B) with plasma lipid levels and CETP activity in ...
متن کاملبررسی ارتباط پلی‌مورفیسم Taq 1B در ژن کلستریل استرترانسفر پروتئین با پارامترهای سندرم متابولیک
Background & aims: Metabolic Syndrome (MetS) is a potential threatening factor for cardiovascular disorders and atherosclerosis which is accompanied by increase in plasma triglyceride, cholesterol, low density lipoproteins (LDL-c), fasting blood sugar (FBS) and low high density lipoproteins (HDL-c). Cholesteryl ester transfer protein (CETP) catalysis transfer of lipids and phospholipids betw...
متن کاملارتباط پلی‌مورفیسم D442G ژن کلسترول استر ترانسفر پروتیین با الگوی لیپیدی و فعالیت CETP در بیماران هیپرکلسترولمی
Background: Hypercholesterolemia is considered a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. Cholesteryl ester transfer protein gene polymorphisms are known to be associated with changes in lipid levels. We investigated the association between a polymorphism in the CETP gene (D442G) with plasma lipid levels and CETP activity in patients with hypercholesterole...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 2000
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s0007114500001434